NEUROPROTECTIVE EFFECT OF TERMINALIA CHEBULA EXTRACTS AND ELLAGIC ACID IN PC12 CELLS
نویسندگان
چکیده
منابع مشابه
Neuroprotective Effect of Terminalia Chebula Extracts and Ellagic Acid in Pc12 Cells
BACKGROUND Alzheimer's disease (AD) is one of the common neurodegenerative disorders among elderly. The purpose of this study was to determine the neuroprotective effect and mechanisms of action underlying the Terminalia chebula extracts and ellagic acid by using beta-amyloid25-35 (Aβ25-35)-induced cell toxicity in an undifferentiated pheochromocytoma (PC12) cell line. MATERIALS AND METHODS T...
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The objectives of this study were to determine phytochemical compositions, chemiluminescence antioxidant activities, and neuroprotective effects on PC12 cells for water, methanol, and 95% ethanol extracts of the air-dried fruit of Terminalia chebula Retzius. The water extract afforded the greatest yield, and total phenolic and tannin content. The methanol extract yielded the greatest total trit...
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MinKyun Na, KiHwan Bae*, Sam Sik Kang, Byung Sun Min, Jae Kuk Yoo, Yuko Kamiryo, Yu-ichiro Senoo, Seiichi Yokoo and Nobuhiko Miwa College of Pharmacy, Chungnam National University, Daejeon, Korea Jakwang Research Institute, Hansaeng Cosmetics Co., Ltd., Nonsan, Korea Natural Products Research Institute, Seoul National University, Seoul, Korea Laboratory of Immunomodulator, Korea Research Instit...
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Objective: This study was conducted to evaluate the possible antioxidant activity and neuroprotective effects of aqueous and methanolic extracts of Althaea officinalis flowers against H2O2-induced oxidative stress in PC12 cells. Material and Methods: The antioxidant potential of extracts was evaluated by radical scavenging activity using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay. For c...
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BACKGROUND Burgeoning antibiotic resistance in Pseudomonas aeruginosa has necessitated the development of anti pathogenic agents that can quench acylhomoserine lactone (AHL) mediated QS with least risk of resistance. This study explores the anti quorum sensing potential of T. chebula Retz. and identification of probable compounds(s) showing anti QS activity and the mechanism of attenuation of P...
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ژورنال
عنوان ژورنال: African Journal of Traditional, Complementary and Alternative medicines
سال: 2017
ISSN: 0189-6016,2505-0044
DOI: 10.21010/ajtcam.v14i4.3